How we think about oncology development.
Short working notes on protocols, data, oversight and leadership. Each links to public sources where regulatory points are made.
All perspectives
Fractional CMO leadership tailored to your specific needs
A practical way to define the mandate of a part-time chief medical officer before the engagement starts.
Read the perspective →Clinical dataReading an oncology dataset from the patient upward
Why clinical data review, interpretation and communication belong together, and how to sequence them.
Read the perspective →Protocol designFive questions before an oncology protocol is finalized
A short checklist for testing whether a protocol answers the clinical question and can be delivered.
Read the perspective →Clinical diligenceWhat a clinical asset assessment should make explicit
The points a clinical assessment of an oncology asset has to make visible for a licensing or investment decision.
Read the perspective →Competitive intelligenceWhat changes after a competitor’s oncology readout?
A way to separate what a new readout reports from what it means for your own program.
Read the perspective →Sponsor oversightFinding the cause of CRO and sponsor delivery problems
How to tell whether a delivery problem sits with the vendor, the sponsor or the protocol.
Read the perspective →Early developmentThe first protocol is only one part of first-trial readiness
Why readiness for a first human study depends on evidence, people and operating decisions as well as the protocol.
Read the perspective →Clinical AIBefore a clinical AI pilot, define what a useful result means
Questions to settle before testing an AI-assisted clinical review tool.
Read the perspective →Tell us about the decision in front of you.
A short, nonconfidential outline is enough: the development stage, the question and the timing. We will reply about fit, expertise and next steps.
Email links open your email application. Nothing is sent until you press send. Please do not include patient information or confidential study materials in a first message.
- 01Outline the needThe decision, the stage of the program and the timing.
- 02Establish fitExpertise, availability, relevant interests and information requirements.
- 03Agree the scopeDeliverables, responsibilities and commercial terms before work begins.